Department of Ophthalmology, Grigore T.
Laryngeal Papillomatosis (Respiratory Papillomas)- For Medical Students
E-mail: moc. We report the detection of HPV 52 in a sample taken from a year-old patient with squamous cell carcinoma of the conjunctiva of the left eye.
- The juvenile laryngeal papillomatosis is the most frequent benign tumour of the larynx.
Джабба вытаращил глаза: - Мидж, дорогая.
The method used for the detection of HPV was real time polymerase chain reaction. The evolution was favorable after surgical removal of the tumor and the patient was explained that long-term follow-up is essential to avoid recurrence.
The detection of human papillomaviruses in histological preparations by using dot-blot hybridization. Rev Roum Virol. Anton G.
laryngeal papilloma lesion Laryngeal papilloma lesion Conjunctiva, eye, human papillomavirus 52, real time polymerase chain reaction, squamous cell carcinoma Human papillomavirus HPV infection is strongly associated laryngeal papilloma lesion anogenital tumors cervix, penis, vulva, vagina, anushead and neck cancers oral cavity, esophagus, larynxand nonmelanoma skin cancers squamous and basal cell carcinoma.
The association between HPV infection and eye tumors is little cancer testicular perros territory. Di Girolamo brings forward a two-hit theory that explains cancerogenesis in OSSN: The first hit is mediated by ultraviolet radiation exposure that causes genetic alteration and the second hit is mediated by HPV infection in the susceptible cells.
laryngeal papilloma lesion Case Report We present a unique case of squamous cell carcinoma of the conjunctiva examined and treated in June The year-old patient presented at the Ophthalmology Department for mild stinging sensation and redness in the left eye for almost 1-year and a half.
He has been treated for laryngeal papilloma lesion last 2 months with dexamethasone eye drops for scleritis by another ophthalmologist.
The patient admits being a heavy smoker for almost 30 years and that in his free time he practices agriculture without using sunglasses.
The lack of a curative treatment and the tendency of the papillomatosis to recur in an extensive manner require an aggressive treatment. Although multiple medical therapies are available, their results are not always the desired ones. That is why nowadays the focus of the therapy is on the surgical approach. The best results may be obtained thru laryngeal papilloma lesion surgeries, with resection of all papilloma foci.
All other ophthalmological findings were normal. Conjunctival culture laryngeal papilloma lesion performed before surgery, and no bacterial infection was found. The CT scan of the head and neck showed no signs of tumor invasion of the orbit or laryngeal papilloma lesion lymph nodes.
The limbic lesion was removed surgically with 2 mm margin of normal tissue and diathermy of the adjacent sclera was done. At the end, the remaining temporal defect was laryngeal papilloma lesion using a supero-nasal conjunctiva graft fixed in position with interrupted and surjet The excised tumor was cut laryngeal papilloma lesion 2 fragments: One for pathology preserved in formalin and one for HPV genotyping preserved in Cobas polymerase chain reaction PCR solution and refrigerated at 4°C until processing.
Histopathology exam showed a moderate differentiated keratinized squamous cell carcinoma of the conjunctiva without koilocytosis [Figs.