Corresponding author: Dr. Maria Alexandra Barbu, e-mail: m.
There is a strong link between the presence of human papillomavirus HPV cervical cancer and its precursors. All patients diagnosed with invasive cervical carcinoma should be evaluated clinically by vaginal exam and rectal imaging by computed tomography, magnetic resonance imaging or PET-CT.
According to some recent studies, the HPV infection may also increase the risk of cardiovascular diseases. Strains of HPV 16 and 18 are strains with a high cancer risk, known to cause almost all cases of cervical cancer while also increasing the risk to develop oropharyngeal cancer. Structura HPV women. Fig 1.
FIGO system is most widely used staging system for cervical cancer. FIGO staging system is mainly based on clinical examination, pelvic examination therefore performed by a clinician with experience, which is critically important.
Basically, in micro invasive carcinoma std.
IA1 the treatment of choice is conservative hpv diagnosis what now excisional conisation or hysterectomy extra fasciala. In invasive cancers in early stages std. IA2, IB1, some IIA the treatment of choice is radical hysterectomy or modified radical hysterectomy, radical trachelectomia if desired fertility preservation or radiotherapy. In locally advanced cancers std.
IB2 to IVA the treatment of choice is radio chemotherapy. Treatment of patients with metastatic disease is primarily systemic chemotherapy, but the patients are encouraged to participate in clinical trials.
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