Cancer de colon metastasis. Traducere "cáncer de colon" în română


Anca Zgură, Laurenţia Galeş, Prof.

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Breast, ovarian, and cervical cancer are the most common cancers diagnosed during pregnancy. The manifestations encountered in colorectal cancer, such as abdominal pain, constipation, vomiting, nausea, rectal bleeding and altered bowel movements, are also found in normal pregnancy.

In this paper, we present a case of colorectal cancer with hepatic metastasis diagnosed in a year-old preganant woman IIG, 1Pat 32 weeks of pregnancy.

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Keywords pregnancy, colorectal cancer, metastasis, teratogencity, chemotherapy Rezumat Incidenţa cancerului colorectal în timpul sarcinii este mică, de un caz la cancer de colon metastasis.

Cancerul mamar, ovarian şi cel cervical sunt cele mai frecvente tipuri de cancer diagnosticate în timpul sarcinii. Manifestările întâlnite în cancerul colorectal, precum dureri abdominale, constipaţie, vărsături, greaţă, sângerări rectale şi tulburări intestinale, se întâlnesc şi în timpul sarcinii normale, făcând dificilă diagnosticarea pe parcursul  sarcinii.

În această lucrare vă prezentăm cazul unei paciente de 36 de ani IIG, 1Pîn săptămâna a a de sarcină, diagnosticată cu cancer colorectal, prezentând şi metastaze hepatice. Cuvinte cheie cancer colorectal metastaze teratogenitate chimioterapie Introduction The incidence cancer de colon metastasis colorectal cancer during pregnancy is reduced, being estimated at approximately one in every preganancies Breast, ovarian and cervical cancer are the most common cancers diagnosed during pregnancy 2.

The manifestations encountered in colorectal cancer, such as abdominal pain, constipation, vomiting, nausea, rectal bleeding and altered bowel movements, are also found in normal pregnancy 5.

Most of the colorectal cancers cancer de colon metastasis missed and are diagnosed in advanced stages. Using the antineoplastic agents in a pregnant patient is a difficult decision, with many of safety and efficacy implications 6. The treatment plan depends on the desire of the pregnant woman, the stage of the disease, the possible teratogenic effects of the antineoplastic agents and abortion We present in this paper a case of colorectal cancer with hepatic metastasis diagnosed in a patient at 32 weeks of pregnancy.

Figure 1.

Traducere "cáncer de colon" în română

She also had constipation and anemia. She was initially evaluated by her gynecologist, who suggested a second opinion from a gastroenterologist, who performed an abdominal and pelvic IRM. The abdominal and cancer de colon metastasis IRM evaluation revealed cancer de colon metastasis hepatomegaly mm cranio caudal right lobe, 97 mm antero-posterior left lobeand more lobular contour space replacement formation.

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The CT scan of the thorax was without secondary pulmonary determinations. There was no family history of cancer. The physical examination at the time was unremarkable, except for normal signs of pregnancy. The patient was anemic at the time of presentation, the hemoglobin level was 9.

Cancerul colorectal în sarcină

After the imagistic and biological evaluation, she was refered to a surgeon, who thought that her pregnancy would make difficult to receive prompt adjuvant therapy.

The patient was only week pregnant at the time of diagnosis. A caesarean section was performed, resulting in the birth cancer de colon metastasis a premature baby, weighing g, who received an Apgar score of 9.

During the same operation, cancer de colon metastasis left hemicolectomy and right cancer de colon metastasis were also performed. The histopatological raport revealed a moderate adenocarcinoma G2six nodes were examinated, but only two were positive.

The histopatological examination of the ovary showed metastasis of moderate adenocarcinoma Krukenberg ovary. Before deciding on the initiation of chemotherapy, cancer gastric simptomatologie patient experienced altered generalized status, medium ascites, cancer de colon metastasis and gambling edema.

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She received a cycle of adjuvant chemotherapy consisting of cetuximab mg. The patient tolerated the therapy with supportive treatment and minimal hematologic and non-hematologic toxicities. After one month, we changed the chemotheray cycle with cetuximab, oxaliplatin and 5-FU, due to the improvement of the recherche de papillomavirus chez lhomme state.

A follow-up CT scan after three months showed evolution in mild numerical regression of liver lesions.

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The hepatomegaly was maintained. Fine fluid blade in dimensional regression. Without bone metastases. The cancer de colon metastasis chemotherapy combined with targeted therapy using cetuximab has been considered for the patient in order to eradicate the metastatic disease.

Discussion Despite the low incidence rate of 0.

Colorectal cancer is among the eight most common malignancies in pregnancy 2. Colorectal cancer in pregnancy represents a serious situation, and there are many challenging issues regarding the diagnosis and management in pregnancy.

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  • Viermi intestinali la copii de 2 ani
  • Cancerul colorectal în sarcină
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Because the signs and simptoms are similar in pregnancy and colorectal cancer, the colorectal cancer can be concealed In our patient, the abdominal pain was misdiagnosed as a sign cancer de colon metastasis simptom of a normal pregnancy. There are limitations and contraindications for using imaging tests during pregnancy.

IRM remains relatively safe in pregnancy and the best option to evaluate the colorectal cancer.

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Serum CEA is an important test used in the evaluation of patients with colorectal cancer CEA levels during pregnancy may be elevated and can be used for monitoring the response of the treatment 15, Due to the fact that colorectal cancer is encoutered in cancer de colon metastasis eldery and rarerly in young patients, it is assumed that there are a number of predisposing factors, such as Lynch syndrome, Peutz-Jeghers syndrome and inflammatory bowel disease Another challenging issue is the treatment, which should be started as early for the mother, and is based on the gestational age and tumor stage.

If diagnosis occurs during the first trimester of pregnancy, it may be expected until the fetus becomes viable, but with significant tumor progression 18, If the diagnosis occurs after the cancer de colon metastasis week of pregnancy, colon resection may be delayed.

Chemotheray is safer in the second and third trimesters, when organogenesis is complete There are cancer de colon metastasis human data for the effect of cetuximab in pregnancy The ovarian metastatic disease from colorectal cancer is another challenge. The incidence of ovarian metastases from colorectal cancer is higher in pregnant women. The survival of the pregnant woman with ovarian metastases is poor. Nesbitt et al.

There are no fetal risk due to the malignancy itself, even in metastasis cases. The pregnant woman with colorectal cancer has a poor prognosis. A review of 15 cases  revealed that all patients with colorectal cancer presented in stage IV, and these patients died cancer de colon metastasis 12 months after delivery Conclusions Colorectal cancer in pregnancy represents a diagnostic and therapeutic challenge.

Because the signs and simptoms are similar in pregnancy and colorectal cancer, the diagnosis of colorectal cancer is often delayed. The therapeutic decison for a pregnant patient with colorectal cancer should involve a multidisciplinary team, and cancer de colon metastasis must papiloma humano ano mujeres taken into account the life of the unborn child and the survival of the mother.

Conflict of interests: The authors declare no conflict cancer de colon metastasis interests. Carcinoma of the colon associated with pregnancy: report of a case. Dis Colon Rectum. Colorectal cancer discovered during pregnancy.

J Gynecol Obstet et Biol Reprod. Cancer and pregnancy: an overview for obstetricians and gynecologists. Am J Obstet Cancer de colon metastasis.

Por la misma razón que no hablo sobre el cáncer de colon. Din același motiv pentru care n-am vorbit ce cancerul de colon. Se había sometido a una operación para el cáncer de colon.

Cancer and pregnancy: What should we know about the management with systemic treatment of pregnant women with cancer? Eur J Cancer. Cancer chemotherapy and pregnancy. J Obstet Gynaecol Can.

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Cardonick E, Iacobucci A. Use of chemotherapy during human pregnancy. Lancet Oncol. Cancer chemotherapeutic agents as human teratogens. Chemotherapy during pregnancy.

Curr Opin Oncol. Antineoplastic drugs. Drugs During Pregnancy and Lactation: treatment options and risk assessment.

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Amsterdam: Academic Press; ; — Management of rectal cancer in pregnant women. Bull Cancer.

Jump to navigation Jump to search Metastaza constă în răspândirea cancerului de la un organ sau parte la un alt organ sau parte care nu este în vecinătatea imediată cu partea bolnavă.

Mechery J, Ikhena SE. Cancer of the descending colon during pregnancy. J Obstet Gynaecol.

Cristian POPESCU vineri, 15 ianuarie Cancerul de colon este considerat boala rasei caucaziene, fiind a doua cauză neoplazică de deces după cancerul pulmonar 1, 2. Neoplaziile colorectale reprezintă o problemă de sănătate publică în majoritatea țărilor europene, în America și chiar în Japonia, afectând atât femeile, cât și bărbații, indiferent de rasă și având o prevalență de 1 la 20 de locuitori în țările dezvoltate. În anulcancerul colo-rectal a afectat aproximativ de mii de persoane, provocând aproximativ Majoritatea cancerelor de colon debutează ca proliferări benigne de celule, sub forma polipilor colonici 3. Statistic, una din patru persoane în vârsta de 50 de ani are polipi localizați în colon, care se pot transforma în timp în cancere de colon.